I'v noticed that if I zone (go through a gateway or doorway that causes the game to pause to load new graphics) while using my mouse to steer, my character always comes out in the new zone on autorun. This happens any time I accidentally keep my fingers on the mouse buttons until the loading starts. While only a minor irritation when this happens in a safe area, it can be deadly if it happens when zoning into a building / tower level where there is a battle. If you're not quick enough to stop the autorun, you can get drawn into the battle before you you can assess your opponents and set your deck appropriately or heal as needed in multi-room towers.
I'v noticed that if I zone (go through a gateway or doorway that causes the game to pause to load new graphics) while using my mouse to steer, my character always comes out in the new zone on autorun. This happens any time I accidentally keep my fingers on the mouse buttons until the loading starts. While only a minor irritation when this happens in a safe area, it can be deadly if it happens when zoning into a building / tower level where there is a battle. If you're not quick enough to stop the autorun, you can get drawn into the battle before you you can assess your opponents and set your deck appropriately or heal as needed in multi-room towers.
So take your finger off the mouse. Problem solved.