Lately, Since I don't craft much, i got rid of my crafter. I haven't bothered to go to talk to the tangletree lady, but her quest is in I believe Krokatopia. How can I get there?
Once you have completed all your required assignments in Wizard City, Merle Ambrose will ask you to investigate Krokotopia.
Once you have been given that quest, you can access the Spiral door by entering Bartleby the World Tree.
After you’ve completed Krokotopia, you can move on to Marleybone, then MooShu, then Dragonspyre, then Celestia. You can visit Grizzleheim at level 5, but cannot return until level 20.
If you want the prize, you have to build the ladder rung by rung. There are no shortcuts.
You have to finish Wizard City to get to Krokotopia.
As a side note, you can get to Krokotopia without doing Colossus Boulevard, but I recommend that you finish Colossus Boulevard, too, before moving on. The experience you get will help you reach a higher level, and there's a Smith somewhere on the Boulevard that Prospector Zeke wants you to find.